Changes in intravascular kininogen during the Jarisch-Herxheimer reaction in secondary syphilis.

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Changes in intravascular complement, kininogen, and histamine during Jarisch-Herxheimer reaction in secondary syphilis.

Nine patients with secondary syphilis and one control subject were observed for eight hours after the administration of penicillin. Serial clinical observations were made, and blood samples were obtained for the analysis of complement, histamine, and kininogen. Six patients showed Jarisch-Herxheimer reactions, the intensities of which were found to parallel certain changes in activity of comple...

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Jarisch-Herxheimer reaction in secondary syphilis

Nine patients with secondary syphilis and one control subject were observed for eight hours after the administration of penicillin. Serial clinical observations were made, and blood samples were obtained for the analysis of complement, histamine, and kininogen. Six patients showed Jarisch-Herxheimer reactions, the intensities of which were found to parallel certain changes in activity of comple...

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The Jarisch-Herxheimer reaction in leptospirosis.

Three patients with leptospirosis whose condition worsened after initiation of antibiotic therapy are reported. Their clinical deterioration appeared to be due to the development of the Jarisch-Herxheimer reaction rather than to progression of their underlying infection. Relevant aspects of the management of patients with leptospirosis are discussed.

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Penicillin-induced Jarisch-Herxheimer reaction.

OBJECTIVE To report a case of Jarisch-Herxheimer reaction (JHR) in a patient with presumed neurosyphilis and HIV. CASE SUMMARY A 45-year-old HIV-positive man (CD4+ count 450 cells/mm(3) and history of AIDS-defining illness) presented with JHR after an initial intravenous dose of penicillin G for presumed neurosyphilis. The patient described feeling cold with worsening headache and chills appr...

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Jarisch-Herxheimer reaction following penicillin treatment of early congenital syphilis.

ever, as an aftermath of the second world war there was a marked increase in the incidence of early acquired syphilis which reached its peak in the year 1946. Not unexpectedly, it resulted in a steep rise in the number of congenital syphilis cases in 1948 and 1949, followed by a gradual fall in the ensuing years to a low level in 1952 (Morton, 1954). Earlier communications on penicillin treatme...

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ژورنال

عنوان ژورنال: Sexually Transmitted Infections

سال: 1982

ISSN: 1368-4973

DOI: 10.1136/sti.58.6.408-a